5SYT

Crystal Structure of ZMPSTE24

Summary for 5SYT

• Entry DOI: 10.2210/pdb5syt/pdb
• Related: 2YPT 4AW6 4IL3
• Descriptor: CAAX prenyl protease 1 homolog, SULFATE ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (10 entities in total)
• Functional Keywords: hydrolase, membrane protein, caax protease, zinc metalloprotease, ste24, isoprenylation, structural genomics, psi-2, protein structure initiative, membrane protein structural biology consortium, mpsbc
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 60959.33

Authors

Clark, K.,Jenkins, J.L.,Fedoriw, N.,Dumont, M.E.,Membrane Protein Structural Biology Consortium (MPSBC) (deposition date: 2016-08-11, release date: 2016-11-02, Last modification date: 2023-10-04)

• Primary citation: Clark, K.M.,Jenkins, J.L.,Fedoriw, N.,Dumont, M.E.; Human CaaX protease ZMPSTE24 expressed in yeast: Structure and inhibition by HIV protease inhibitors.; Protein Sci., 26:242-257, 2017; PubMed: 27774687; DOI: 10.1002/pro.3074

Experimental method

X-RAY DIFFRACTION (2 Å)