5RLU

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 helicase in complex with Z744754722

Summary for 5RLU

• Entry DOI: 10.2210/pdb5rlu/pdb
• Group deposition: PanDDA analysis group deposition (G_1002164)
• Descriptor: Helicase, 2-(thiophen-2-yl)-1H-imidazole, ZINC ION, ... (5 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 2
• Total formula weight: 134933.80

Authors

Newman, J.A.,Yosaatmadja, Y.,Douangamath, A.,Aimon, A.,Powell, A.J.,Dias, A.,Fearon, D.,Dunnett, L.,Brandao-Neto, J.,Krojer, T.,Skyner, R.,Gorrie-Stone, T.,Thompson, W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2020-09-16, release date: 2020-09-30, Last modification date: 2024-05-22)

• Primary citation: Newman, J.A.,Douangamath, A.,Yadzani, S.,Yosaatmadja, Y.,Aimon, A.,Brandao-Neto, J.,Dunnett, L.,Gorrie-Stone, T.,Skyner, R.,Fearon, D.,Schapira, M.,von Delft, F.,Gileadi, O.; Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.; Nat Commun, 12:4848-4848, 2021; PubMed: 34381037; DOI: 10.1038/s41467-021-25166-6

Experimental method

X-RAY DIFFRACTION (2.347 Å)