5QXI

PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC587

Summary for 5QXI

• Entry DOI: 10.2210/pdb5qxi/pdb
• Group deposition: PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118)
• Descriptor: ATPase family AAA domain-containing protein 2, (4R,4aS,7aS,9S)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3',4':5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol, (4R,4aR,7aS,9R)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3',4':5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol, ... (6 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16299.39

Authors

Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (deposition date: 2020-02-11, release date: 2020-04-08, Last modification date: 2024-03-06)

• Primary citation: Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F.; PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.64 Å)