5OOH
Human biliverdin IX beta reductase: NADP/Erythrosin extra bluish ternary complex
Summary for 5OOH
Entry DOI | 10.2210/pdb5ooh/pdb |
Descriptor | Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | biliverdin reductase, oxidoreductase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P30043 |
Total number of polymer chains | 1 |
Total formula weight | 23819.74 |
Authors | Manso, J.A.,Pereira, P.J.B. (deposition date: 2017-08-07, release date: 2018-03-07, Last modification date: 2024-01-17) |
Primary citation | Nesbitt, N.M.,Zheng, X.,Li, Z.,Manso, J.A.,Yen, W.Y.,Malone, L.E.,Ripoll-Rozada, J.,Pereira, P.J.B.,Mantle, T.J.,Wang, J.,Bahou, W.F. In silicoand crystallographic studies identify key structural features of biliverdin IX beta reductase inhibitors having nanomolar potency. J. Biol. Chem., 293:5431-5446, 2018 Cited by PubMed: 29487133DOI: 10.1074/jbc.RA118.001803 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
Download full validation report