5OKP
Crystal structure of human SHIP2 Phosphatase-C2 double mutant F593D/L597D
Summary for 5OKP
Entry DOI | 10.2210/pdb5okp/pdb |
Descriptor | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | ship2, phosphatase, c2, phosphatidylinositol (3, 4, 5)-triphosphate, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytosol: O15357 |
Total number of polymer chains | 1 |
Total formula weight | 52968.62 |
Authors | Le Coq, J.,Lietha, D. (deposition date: 2017-07-25, release date: 2017-08-23, Last modification date: 2024-05-08) |
Primary citation | Le Coq, J.,Camacho-Artacho, M.,Velazquez, J.V.,Santiveri, C.M.,Gallego, L.H.,Campos-Olivas, R.,Dolker, N.,Lietha, D. Structural basis for interdomain communication in SHIP2 providing high phosphatase activity. Elife, 6:-, 2017 Cited by PubMed: 28792888DOI: 10.7554/eLife.26640 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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