5OJ7

Sirtuin 4 orthologue from Xenopus Tropicalis in complex with ADP-ribose

Summary for 5OJ7

Entry DOI	10.2210/pdb5oj7/pdb
Related	5OJN 5OJO
Descriptor	NAD-dependent protein deacylase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ZINC ION, ... (6 entities in total)
Functional Keywords	sirt4 deacylase posttranslational modification, hydrolase
Biological source	Xenopus tropicalis (Western clawed frog)
Cellular location	Mitochondrion matrix : Q28CB4
Total number of polymer chains	1
Total formula weight	33065.49
Authors	Pannek, M.,Steegborn, C. (deposition date: 2017-07-20, release date: 2017-11-29, Last modification date: 2024-01-17)
Primary citation	Pannek, M.,Simic, Z.,Fuszard, M.,Meleshin, M.,Rotili, D.,Mai, A.,Schutkowski, M.,Steegborn, C. Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features. Nat Commun, 8:1513-1513, 2017 Cited by PubMed: 29138502 DOI: 10.1038/s41467-017-01701-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation