5O9Q
Crystal structure of ScGas2 in complex with compound 6
Summary for 5O9Q
Entry DOI | 10.2210/pdb5o9q/pdb |
Descriptor | 1,3-beta-glucanosyltransferase GAS2, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[4-(phenylmethoxymethyl)-1,2,3-triazol-1-yl]oxan-4-yl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-oxane-3,4,5-triol, ... (4 entities in total) |
Functional Keywords | aspergillus fumigatus, afgel4, scgas2, transglycosylases, glucanosyltransferases, cell wall remodeling, fungal cell wall, transferase |
Biological source | Saccharomyces cerevisiae S288c |
Cellular location | Cell membrane ; Lipid-anchor, GPI-anchor : Q06135 |
Total number of polymer chains | 1 |
Total formula weight | 63606.07 |
Authors | Delso, I.,Valero-Gonzalez, J.,Gomollon-Bel, F.,Castro-Lopez, J.,Fang, W.,Navratilova, I.,Van Aalten, D.,Tejero, T.,Merino, P.,Hurtado-Guerrero, R. (deposition date: 2017-06-20, release date: 2018-05-02, Last modification date: 2024-01-17) |
Primary citation | Delso, I.,Valero-Gonzalez, J.,Gomollon-Bel, F.,Castro-Lopez, J.,Fang, W.,Navratilova, I.,van Aalten, D.M.F.,Tejero, T.,Merino, P.,Hurtado-Guerrero, R. Inhibitors against Fungal Cell Wall Remodeling Enzymes. ChemMedChem, 13:128-132, 2018 Cited by PubMed: 29164827DOI: 10.1002/cmdc.201700720 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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