5O6T
BIRC4 RING in complex with dimeric ubiquitin variant
Summary for 5O6T
Entry DOI | 10.2210/pdb5o6t/pdb |
Descriptor | E3 ubiquitin-protein ligase XIAP, Polyubiquitin-B, ZINC ION, ... (5 entities in total) |
Functional Keywords | e3 ring ligase, ubiquitin variant, ligase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P98170 Ubiquitin: Cytoplasm : P0CG47 |
Total number of polymer chains | 4 |
Total formula weight | 33606.43 |
Authors | Gabrielsen, M.,Buetow, L.,Huang, D.T. (deposition date: 2017-06-07, release date: 2017-11-01, Last modification date: 2024-01-17) |
Primary citation | Gabrielsen, M.,Buetow, L.,Nakasone, M.A.,Ahmed, S.F.,Sibbet, G.J.,Smith, B.O.,Zhang, W.,Sidhu, S.S.,Huang, D.T. A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol. Cell, 68:456-470.e10, 2017 Cited by PubMed: 29053960DOI: 10.1016/j.molcel.2017.09.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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