5O11
Crystal structure of PIM1 kinase in complex with small-molecule inhibitor
Summary for 5O11
| Entry DOI | 10.2210/pdb5o11/pdb |
| Descriptor | Serine/threonine-protein kinase pim-1, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, IMIDAZOLE, ... (6 entities in total) |
| Functional Keywords | kinase, cx-4945, pim1, transferase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
| Total number of polymer chains | 1 |
| Total formula weight | 35172.49 |
| Authors | Bogusz, J.,Dubin, G. (deposition date: 2017-05-17, release date: 2017-11-01, Last modification date: 2024-01-17) |
| Primary citation | Bogusz, J.,Zrubek, K.,Rembacz, K.P.,Grudnik, P.,Golik, P.,Romanowska, M.,Wladyka, B.,Dubin, G. Structural analysis of PIM1 kinase complexes with ATP-competitive inhibitors. Sci Rep, 7:13399-13399, 2017 Cited by PubMed: 29042609DOI: 10.1038/s41598-017-13557-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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