5NMI

Cytochrome bc1 bound to the inhibitor MJM170

Summary for 5NMI

• Entry DOI: 10.2210/pdb5nmi/pdb
• Descriptor: Cytochrome b-c1 complex subunit 1, mitochondrial, ARG-ASN-TRP-VAL-PRO-THR-ALA-GLN-LEU-TRP-GLY-ALA-VAL-GLY-ALA-VAL-GLY-LEU-VAL-SER-ALA-THR, PROTOPORPHYRIN IX CONTAINING FE, ... (16 entities in total)
• Functional Keywords: membrane protein, inhibitor complex
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 22
• Total formula weight: 549501.04

Authors

Capper, N.J.,Antonyuk, S.V.,Hasnain, S.S. (deposition date: 2017-04-05, release date: 2017-06-14, Last modification date: 2018-12-19)

• Primary citation: McPhillie, M.,Zhou, Y.,El Bissati, K.,Dubey, J.,Lorenzi, H.,Capper, M.,Lukens, A.K.,Hickman, M.,Muench, S.,Verma, S.K.,Weber, C.R.,Wheeler, K.,Gordon, J.,Sanders, J.,Moulton, H.,Wang, K.,Kim, T.K.,He, Y.,Santos, T.,Woods, S.,Lee, P.,Donkin, D.,Kim, E.,Fraczek, L.,Lykins, J.,Esaa, F.,Alibana-Clouser, F.,Dovgin, S.,Weiss, L.,Brasseur, G.,Wirth, D.,Kent, M.,Hood, L.,Meunieur, B.,Roberts, C.W.,Hasnain, S.S.,Antonyuk, S.V.,Fishwick, C.,McLeod, R.; New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.; Sci Rep, 6:29179-, 2016; PubMed: 27412848; DOI: 10.1038/srep29179

Experimental method

X-RAY DIFFRACTION (3.5 Å)