5NFP
Glucocorticoid Receptor in complex with budesonide
Summary for 5NFP
Entry DOI | 10.2210/pdb5nfp/pdb |
Descriptor | Glucocorticoid receptor, Nuclear receptor coactivator 2, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... (7 entities in total) |
Functional Keywords | glucocorticoid receptor, nuclear hormone receptor, steroid receptor, ligand complex, peptide complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform Alpha: Cytoplasm . Isoform Beta: Nucleus . Isoform Alpha-B: Nucleus : P04150 Nucleus: Q15596 |
Total number of polymer chains | 2 |
Total formula weight | 35095.64 |
Authors | Edman, K.,Wissler, L. (deposition date: 2017-03-15, release date: 2017-10-04, Last modification date: 2024-01-17) |
Primary citation | Hemmerling, M.,Nilsson, S.,Edman, K.,Eirefelt, S.,Russell, W.,Hendrickx, R.,Johnsson, E.,Karrman Mardh, C.,Berger, M.,Rehwinkel, H.,Abrahamsson, A.,Dahmen, J.,Eriksson, A.R.,Gabos, B.,Henriksson, K.,Hossain, N.,Ivanova, S.,Jansson, A.H.,Jensen, T.J.,Jerre, A.,Johansson, H.,Klingstedt, T.,Lepisto, M.,Lindsjo, M.,Mile, I.,Nikitidis, G.,Steele, J.,Tehler, U.,Wissler, L.,Hansson, T. Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases. J. Med. Chem., 60:8591-8605, 2017 Cited by PubMed: 28937774DOI: 10.1021/acs.jmedchem.7b01215 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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