5NE3

L2 class A serine-beta-lactamase complexed with avibactam

Summary for 5NE3

Entry DOI	10.2210/pdb5ne3/pdb
Descriptor	Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total)
Functional Keywords	beta-lactamase, carbapenemase, inhibitor, avibactam, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Stenotrophomonas maltophilia K279a
Total number of polymer chains	2
Total formula weight	59170.97
Authors	Hinchliffe, P.,Calvopina, K.,Spencer, J. (deposition date: 2017-03-09, release date: 2017-09-13, Last modification date: 2024-01-17)
Primary citation	Calvopina, K.,Hinchliffe, P.,Brem, J.,Heesom, K.J.,Johnson, S.,Cain, R.,Lohans, C.T.,Fishwick, C.W.G.,Schofield, C.J.,Spencer, J.,Avison, M.B. Structural/mechanistic insights into the efficacy of nonclassical beta-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates. Mol. Microbiol., 106:492-504, 2017 Cited by PubMed: 28876489 DOI: 10.1111/mmi.13831 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation