5N92

Crystal Structure of Human IL-17AF

Summary for 5N92

Entry DOI	10.2210/pdb5n92/pdb
Descriptor	Interleukin-17A, Interleukin-17F, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	cystine-knot, heterodimer, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	31412.56
Authors	Rondeau, J.-M.,Goepfert, A. (deposition date: 2017-02-24, release date: 2017-09-06, Last modification date: 2020-07-29)
Primary citation	Goepfert, A.,Lehmann, S.,Wirth, E.,Rondeau, J.M. The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties. Sci Rep, 7:8906-8906, 2017 Cited by PubMed: 28827714 DOI: 10.1038/s41598-017-08360-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation