5N88
Crystal structure of antibody bound to viral protein
Summary for 5N88
Entry DOI | 10.2210/pdb5n88/pdb |
Descriptor | VH59 antibody, PC4 and SFRS1-interacting protein, ... (4 entities in total) |
Functional Keywords | mll: hiv: intracellular antibody: integrase: ledgf, aids, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 46424.86 |
Authors | Bao, L.,Hannon, C.,Cruz-Migoni, A.,Ptchelkine, D.,Sun, M.-y.,Derveni, M.,Bunjobpol, W.,Chambers, J.S.,Simmons, A.,Phillips, S.E.V.,Rabbitts, T.H. (deposition date: 2017-02-23, release date: 2017-12-20, Last modification date: 2019-10-16) |
Primary citation | Bao, L.,Hannon, C.,Cruz-Mignoni, A.,Ptchelkine, D.,Sun, M.Y.,Miller, A.,Bunjobpol, W.,Quevedo, C.E.,Derveni, M.,Chambers, J.,Simmons, A.,Phillips, S.E.V.,Rabbitts, T.H. Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein. Sci Rep, 7:16869-16869, 2017 Cited by PubMed: 29203900DOI: 10.1038/s41598-017-16742-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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