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5MZ4

Crystal Structure of full-lengh CSFV NS3/4A

Replaces:  5LKL
Summary for 5MZ4
Entry DOI10.2210/pdb5mz4/pdb
Related5lkl
DescriptorGenome polyprotein,Genome polyprotein (2 entities in total)
Functional Keywordsflaviviridae, ns3/ns4a, protease/helicase, viral protein
Biological sourceClassical swine fever virus (strain Alfort) (CSFV)
More
Cellular locationE(rns) glycoprotein: Host membrane; Peripheral membrane protein. Envelope glycoprotein E2: Host cell surface . Cysteine protease NS2: Host membrane ; Multi-pass membrane protein : P19712
Total number of polymer chains2
Total formula weight167338.66
Authors
Tortorici, M.A.,Rey, F.A. (deposition date: 2017-01-30, release date: 2017-02-15, Last modification date: 2024-01-17)
Primary citationDubrau, D.,Tortorici, M.A.,Rey, F.A.,Tautz, N.
A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis.
PLoS Pathog., 13:e1006134-e1006134, 2017
Cited by
PubMed: 28151973
DOI: 10.1371/journal.ppat.1006134
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.048 Å)
Structure validation

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