5MS4
Kallikrein-related peptidase 8 leupeptin inhibitor complex
Summary for 5MS4
Entry DOI | 10.2210/pdb5ms4/pdb |
Related PRD ID | PRD_000216 |
Descriptor | Kallikrein-8, LEUPEPTIN, TERTIARY-BUTYL ALCOHOL, ... (5 entities in total) |
Functional Keywords | trypsin-like serine protease, aldehyde inhibitor, ca2+ complex, synaptic remodeling, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 100039.45 |
Authors | Debela, M.,Magdolen, V.,Skala, W.,Bode, W.,Brandstetter, H.,Goettig, P. (deposition date: 2016-12-30, release date: 2018-01-17, Last modification date: 2019-10-09) |
Primary citation | Debela, M.,Magdolen, V.,Skala, W.,Elsasser, B.,Schneider, E.L.,Craik, C.S.,Biniossek, M.L.,Schilling, O.,Bode, W.,Brandstetter, H.,Goettig, P. Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Sci Rep, 8:10705-10705, 2018 Cited by PubMed: 30013126DOI: 10.1038/s41598-018-29058-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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