5MJT

Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide

Summary for 5MJT

• Entry DOI: 10.2210/pdb5mjt/pdb
• Descriptor: Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (9 entities in total)
• Functional Keywords: coagulation, blood clotting, convertion of fibrinogen to fibrin, blood clotting inhibitor, preorganization, glycosilation, blood, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P09945
• Total number of polymer chains: 3
• Total formula weight: 36582.87

Authors

Marca, A.,Sandner, A.,Heine, A.,Klebe, G. (deposition date: 2016-12-01, release date: 2017-12-20)

• Primary citation: Marca, A.,Ngo, K.,Sandner, A.,Heine, A.,Klebe, G.; Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide; to be published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)