5M4D

Alpha-amino epsilon-caprolactam racemase K241A mutant in complex with D-ACL (external aldimine)

Summary for 5M4D

• Entry DOI: 10.2210/pdb5m4d/pdb
• Related: 5M46
• Descriptor: Aminotransferase class-III, [6-methyl-5-oxidanyl-4-[(~{E})-[(3~{R})-2-oxidanylideneazepan-3-yl]iminomethyl]pyridin-3-yl]methyl dihydrogen phosphate, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: plp, racemase, isomerase
• Biological source: Rhizobium freirei PRF 81
• Total number of polymer chains: 1
• Total formula weight: 46465.66

Authors

Frese, A.,Sutton, P.W.,Turkenburg, J.P.,Grogan, G. (deposition date: 2016-10-18, release date: 2017-04-19, Last modification date: 2024-01-17)

• Primary citation: Frese, A.,Sutton, P.W.,Turkenburg, J.P.,Grogan, G.; Snapshots of the Catalytic Cycle of the Industrial Enzyme alpha-Amino-epsilon-Caprolactam Racemase (ACLR) Observed Using X-ray Crystallography; Acs Catalysis, 7:1045-1048, 2017; DOI: 10.1021/acscatal.6b03056

Experimental method

X-RAY DIFFRACTION (1.93 Å)