5M3V

BEAT Fc

Summary for 5M3V

• Entry DOI: 10.2210/pdb5m3v/pdb
• Descriptor: Ig gamma-1 chain C region,Ig gamma-3 chain C region, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: antibody tcr bispecific interface, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted : P01860 P01857
• Total number of polymer chains: 2
• Total formula weight: 55255.83

Authors

Skegro, D.,Stutz, C.,Bourquin, F.,Blein, S. (deposition date: 2016-10-17, release date: 2017-05-10, Last modification date: 2024-01-17)

• Primary citation: Skegro, D.,Stutz, C.,Ollier, R.,Svensson, E.,Wassmann, P.,Bourquin, F.,Monney, T.,Gn, S.,Blein, S.; Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies.; J. Biol. Chem., 292:9745-9759, 2017; PubMed: 28450393; DOI: 10.1074/jbc.M117.782433

Experimental method

X-RAY DIFFRACTION (1.97 Å)