5LXG

Revised crystal structure of the human adiponectin receptor 1 in an open conformation

Replaces:  3WXV

Summary for 5LXG

• Entry DOI: 10.2210/pdb5lxg/pdb
• Descriptor: Adiponectin receptor protein 1, V REGION HEAVY CHAIN, V REGION LIGHT CHAIN, ... (6 entities in total)
• Functional Keywords: progestin and adipoq receptor family, integral membrane protein, 7tm, ceramidase, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 60106.82

Authors

Leyrat, C.,Vasiliauskaite-Brooks, I.,Granier, S. (deposition date: 2016-09-21, release date: 2017-03-22, Last modification date: 2024-01-17)

• Primary citation: Vasiliauskaite-Brooks, I.,Sounier, R.,Rochaix, P.,Bellot, G.,Fortier, M.,Hoh, F.,De Colibus, L.,Bechara, C.,Saied, E.M.,Arenz, C.,Leyrat, C.,Granier, S.; Structural insights into adiponectin receptors suggest ceramidase activity.; Nature, 6:120-123, 2017; PubMed: 28329765; DOI: 10.1038/nature21714

Experimental method

X-RAY DIFFRACTION (2.73 Å)