5LHA

Amine transaminase crystal structure from an uncultivated Pseudomonas species in the PMP-bound form

Summary for 5LHA

• Entry DOI: 10.2210/pdb5lha/pdb
• Descriptor: OMEGA TRANSAMINASE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• Functional Keywords: transaminase, aminotransferase, pyridoxamine phosphate, plp-dependent enzyme fold type 1, transferase
• Biological source: Pseudomonas sp.
• Total number of polymer chains: 4
• Total formula weight: 199274.57

Authors

Reddem, E.,Thunnissen, A.M.W.H. (deposition date: 2016-07-10, release date: 2017-03-22, Last modification date: 2024-05-08)

• Primary citation: Borner, T.,Ramisch, S.,Reddem, E.,Bartsch, S.,Vogel, A.,Thunnissen, A.M.W.H.,Adlercreutz, P.,Grey, C.; Explaining Operational Instability of Amine Transaminases: Substrate-Induced Inactivation Mechanism and Influence of Quaternary Structure on Enzyme-Cofactor Intermediate Stability.; Acs Catalysis, 7:1259-1269, 2017; DOI: 10.1021/acscatal.6b02100

Experimental method

X-RAY DIFFRACTION (1.89 Å)