5L46
Crystal structure of human dimethylglycine-dehydrogenase
Summary for 5L46
Entry DOI | 10.2210/pdb5l46/pdb |
Descriptor | Dimethylglycine dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | electron transfer, covalent flavinylation, oxidoreductase, one-carbon metabolism |
Biological source | Homo sapiens (Human) |
Cellular location | Mitochondrion: Q9UI17 |
Total number of polymer chains | 2 |
Total formula weight | 190190.12 |
Authors | Hromic, A.,Pavkov-Keller, T.,Gruber, K. (deposition date: 2016-05-25, release date: 2016-08-17, Last modification date: 2024-01-10) |
Primary citation | Augustin, P.,Hromic, A.,Pavkov-Keller, T.,Gruber, K.,Macheroux, P. Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant. Febs J., 283:3587-3603, 2016 Cited by PubMed: 27486859DOI: 10.1111/febs.13828 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.09 Å) |
Structure validation
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