5L21

Crystal structure of BoNT/A receptor binding domain in complex with VHH C2

Summary for 5L21

• Entry DOI: 10.2210/pdb5l21/pdb
• Descriptor: Botulinum neurotoxin type A, VHH-C2 (3 entities in total)
• Functional Keywords: neutralizing antibody; vhh; botulinum neurotoxin; bont-a-vhh complex, toxin
• Biological source: Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A); More
• Total number of polymer chains: 2
• Total formula weight: 63204.32

Authors

Yao, G.,Jin, R. (deposition date: 2016-07-29, release date: 2017-08-09, Last modification date: 2023-10-04)

• Primary citation: Yao, G.,Lam, K.H.,Weisemann, J.,Peng, L.,Krez, N.,Perry, K.,Shoemaker, C.B.,Dong, M.,Rummel, A.,Jin, R.; A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.; Sci Rep, 7:7438-7438, 2017; PubMed: 28785006; DOI: 10.1038/s41598-017-07457-5

Experimental method

X-RAY DIFFRACTION (1.68 Å)