5L0O

IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions

Summary for 5L0O

Entry DOI	10.2210/pdb5l0o/pdb
Related	3I6X
Descriptor	Ras GTPase-activating-like protein IQGAP1 (1 entity in total)
Functional Keywords	calponin homology, disulfide-bonded dimer, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	89445.61
Authors	Liu, J.,Worthylake, D. (deposition date: 2016-07-27, release date: 2016-09-28, Last modification date: 2023-10-04)
Primary citation	Liu, J.,Kurella, V.B.,LeCour, L.,Vanagunas, T.,Worthylake, D.K. The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin. Biochemistry, 55:6433-6444, 2016 Cited by PubMed: 27798963 DOI: 10.1021/acs.biochem.6b00745 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.36 Å)

Structure validation