5KWW
Crystal Structure of Inhibitor JNJ-53718678 In Complex with Prefusion RSV F Glycoprotein
Summary for 5KWW
Entry DOI | 10.2210/pdb5kww/pdb |
Descriptor | Fusion glycoprotein F0, Envelope glycoprotein chimera, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (6 entities in total) |
Functional Keywords | class i viral fusion protein, respiratory syncytial virus, viral protein, fusion inhibitor, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Human respiratory syncytial virus More |
Total number of polymer chains | 1 |
Total formula weight | 65108.39 |
Authors | McLellan, J.S.,Battles, M.B.,Arnoult, E.,Roymans, D.,Langedijk, J.P. (deposition date: 2016-07-19, release date: 2017-08-02, Last modification date: 2023-10-04) |
Primary citation | Roymans, D.,Alnajjar, S.S.,Battles, M.B.,Sitthicharoenchai, P.,Furmanova-Hollenstein, P.,Rigaux, P.,Berg, J.V.D.,Kwanten, L.,Ginderen, M.V.,Verheyen, N.,Vranckx, L.,Jaensch, S.,Arnoult, E.,Voorzaat, R.,Gallup, J.M.,Larios-Mora, A.,Crabbe, M.,Huntjens, D.,Raboisson, P.,Langedijk, J.P.,Ackermann, M.R.,McLellan, J.S.,Vendeville, S.,Koul, A. Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor. Nat Commun, 8:167-167, 2017 Cited by PubMed: 28761099DOI: 10.1038/s41467-017-00170-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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