5KQU

Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries

Summary for 5KQU

Entry DOI	10.2210/pdb5kqu/pdb
Related	5KQT 5KQW 5KR3 5KR4 5KR5 5KR6
Descriptor	4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
Functional Keywords	phylogenetics, directed evolution, transaminase, protein engineering, transferase
Biological source	Pseudomonas
Total number of polymer chains	6
Total formula weight	313537.39
Authors	Wilding, M.,Newman, J.,Peat, T.S.,Scott, C. (deposition date: 2016-07-06, release date: 2017-07-12, Last modification date: 2023-10-04)
Primary citation	Wilding, M.,Peat, T.S.,Kalyaanamoorthy, S.,Newman, J.,Scott, C.,Jermiin, L.S. Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction Green Chemistry, 19:5375-, 2017 Cited by DOI: 10.1039/c7gc02343j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.62 Å)

Structure validation