5K6E

Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with SBI0654919

Summary for 5K6E

• Entry DOI: 10.2210/pdb5k6e/pdb
• Descriptor: Nuclear receptor ROR-gamma, 2-chloranyl-6-fluoranyl-~{N}-[(2~{R})-4-(4-fluorophenyl)sulfonyl-2-(hydroxymethyl)-2,3-dihydro-1,4-benzoxazin-6-yl]benzamide (3 entities in total)
• Functional Keywords: double helix, signaling protein-inhibitor complex, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P51449
• Total number of polymer chains: 2
• Total formula weight: 58432.37

Authors

Lu, J.,Rastinejad, F. (deposition date: 2016-05-24, release date: 2017-05-31, Last modification date: 2023-09-27)

• Primary citation: Lu, J.,Rastinejad, F.; Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with SBI0654919; To be published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)