5K0T
Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1415
Replaces: 4PPWSummary for 5K0T
Entry DOI | 10.2210/pdb5k0t/pdb |
Related | 5K0S |
Descriptor | Methionine--tRNA ligase, 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | ssgcid, metrs, methionyl-trna synthetase, brucella melitensis, protein biosynthesis, structural genomics, seattle structural genomics center for infectious disease, ligase |
Biological source | Brucella suis biovar 1 (strain 1330) |
Cellular location | Cytoplasm : P59078 |
Total number of polymer chains | 3 |
Total formula weight | 182553.36 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2016-05-17, release date: 2016-05-25, Last modification date: 2023-09-27) |
Primary citation | Ojo, K.K.,Ranade, R.M.,Zhang, Z.,Dranow, D.M.,Myers, J.B.,Choi, R.,Nakazawa Hewitt, S.,Edwards, T.E.,Davies, D.R.,Lorimer, D.,Boyle, S.M.,Barrett, L.K.,Buckner, F.S.,Fan, E.,Van Voorhis, W.C. Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One, 11:e0160350-e0160350, 2016 Cited by PubMed: 27500735DOI: 10.1371/journal.pone.0160350 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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