5JXS
Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus
Summary for 5JXS
Entry DOI | 10.2210/pdb5jxs/pdb |
Descriptor | RNA dependent RNA polymerase, RNA Template, RNA Primer, ... (5 entities in total) |
Functional Keywords | rna-dependent rna polymerase picornavirus foot and mouth disease virus, transferase |
Biological source | Foot-and-mouth disease virus (FMDV) More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3B-1: Virion . Protein 3B-2: Virion . Protein 3B-3: Virion . Picornain 3C: Host cytoplasm . RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P03311 |
Total number of polymer chains | 3 |
Total formula weight | 58564.39 |
Authors | Verdaguer, N.,Ferrer-Orta, C. (deposition date: 2016-05-13, release date: 2016-06-01, Last modification date: 2024-01-10) |
Primary citation | Herod, M.R.,Ferrer-Orta, C.,Loundras, E.A.,Ward, J.C.,Verdaguer, N.,Rowlands, D.J.,Stonehouse, N.J. Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication. J.Virol., 90:6864-6883, 2016 Cited by PubMed: 27194768DOI: 10.1128/JVI.00469-16 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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