5JSG
Crystal structure of Spindlin1 bound to compound EML405
Summary for 5JSG
Entry DOI | 10.2210/pdb5jsg/pdb |
Related | 5JSJ |
Descriptor | Spindlin-1, [2-(phenylamino)-1,4-phenylene]bis({4-[2-(pyrrolidin-1-yl)ethyl]piperidin-1-yl}methanone), MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | sh3-like, beta barrel, cell cycle |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9Y657 |
Total number of polymer chains | 2 |
Total formula weight | 52286.35 |
Authors | |
Primary citation | Bae, N.,Viviano, M.,Su, X.,Lv, J.,Cheng, D.,Sagum, C.,Castellano, S.,Bai, X.,Johnson, C.,Khalil, M.I.,Shen, J.,Chen, K.,Li, H.,Sbardella, G.,Bedford, M.T. Developing Spindlin1 small-molecule inhibitors by using protein microarrays Nat. Chem. Biol., 13:750-756, 2017 Cited by PubMed: 28504676DOI: 10.1038/nchembio.2377 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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