5JEJ
Phosphorylated STING in complex with IRF-3 CTD
Summary for 5JEJ
Entry DOI | 10.2210/pdb5jej/pdb |
Related | 5JEK 5JEL 5JEM 5JEO 5JER |
Descriptor | Stimulator of interferon genes protein, Interferon regulatory factor 3 (3 entities in total) |
Functional Keywords | innate immunity, signaling, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Endoplasmic reticulum membrane ; Multi- pass membrane protein : Q86WV6 Cytoplasm : Q14653 |
Total number of polymer chains | 5 |
Total formula weight | 66539.92 |
Authors | |
Primary citation | Zhao, B.,Shu, C.,Gao, X.,Sankaran, B.,Du, F.,Shelton, C.L.,Herr, A.B.,Ji, J.Y.,Li, P. Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins. Proc.Natl.Acad.Sci.USA, 113:E3403-E3412, 2016 Cited by PubMed: 27302953DOI: 10.1073/pnas.1603269113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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