5JAW

Structure of a beta galactosidase with inhibitor

Summary for 5JAW

• Entry DOI: 10.2210/pdb5jaw/pdb
• Descriptor: Beta-galactosidase, putative, bgl35A, (1S,2S,3S,4S,5R,6R)-5-amino-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, SODIUM ION, ... (5 entities in total)
• Functional Keywords: beta galactosidase, inhibitor, aziridine, hydrolase
• Biological source: Cellvibrio japonicus (strain Ueda107)
• Total number of polymer chains: 8
• Total formula weight: 499195.56

Authors

Offen, W.,Davies, G. (deposition date: 2016-04-12, release date: 2017-05-10, Last modification date: 2024-01-10)

• Primary citation: Schroder, S.P.,van de Sande, J.W.,Kallemeijn, W.W.,Kuo, C.L.,Artola, M.,van Rooden, E.J.,Jiang, J.,Beenakker, T.J.M.,Florea, B.I.,Offen, W.A.,Davies, G.J.,Minnaard, A.J.,Aerts, J.M.F.G.,Codee, J.D.C.,van der Marel, G.A.,Overkleeft, H.S.; Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.; Chem. Commun. (Camb.), 53:12528-12531, 2017; PubMed: 29116266; DOI: 10.1039/c7cc07730k

Experimental method

X-RAY DIFFRACTION (1.6 Å)