5IRC

p190A GAP domain complex with RhoA

Summary for 5IRC

Entry DOI	10.2210/pdb5irc/pdb
Descriptor	Rho GTPase-activating protein 35, Transforming protein RhoA, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	protein-protein complex, transition state, gtpase, gap domain, protein binding
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	4
Total formula weight	89458.46
Authors	Derewenda, U.,Derewenda, Z. (deposition date: 2016-03-12, release date: 2016-08-17, Last modification date: 2019-12-25)
Primary citation	Amin, E.,Jaiswal, M.,Derewenda, U.,Reis, K.,Nouri, K.,Koessmeier, K.T.,Aspenstrom, P.,Somlyo, A.V.,Dvorsky, R.,Ahmadian, M.R. Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS. J.Biol.Chem., 291:20353-20371, 2016 Cited by PubMed: 27481945 DOI: 10.1074/jbc.M116.736967 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation