5IOH

RepoMan-PP1a (protein phosphatase 1, alpha isoform) holoenzyme complex

Summary for 5IOH

• Entry DOI: 10.2210/pdb5ioh/pdb
• Related: 5INB 5J28
• Descriptor: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Cell division cycle-associated protein 2 (3 entities in total)
• Functional Keywords: pp1 alpha; repoman, ki-67; phosphatase, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 82370.40

Authors

Kumar, G.S.,Peti, W.,Page, R. (deposition date: 2016-03-08, release date: 2016-10-05, Last modification date: 2023-09-27)

• Primary citation: Kumar, G.S.,Gokhan, E.,De Munter, S.,Bollen, M.,Vagnarelli, P.,Peti, W.,Page, R.; The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.; Elife, 5:-, 2016; PubMed: 27572260; DOI: 10.7554/eLife.16539

Experimental method

X-RAY DIFFRACTION (2.566 Å)