5IIN

Crystal structure of the pre-catalytic ternary extension complex of DNA polymerase lambda with an 8-oxo-dG:dC base-pair

Summary for 5IIN

• Entry DOI: 10.2210/pdb5iin/pdb
• Related: 5III 5IIJ 5IIK 5IIL 5IIM 5IIO
• Descriptor: DNA polymerase lambda, DNA (5'-D(P*GP*CP*CP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... (8 entities in total)
• Functional Keywords: transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q9UGP5
• Total number of polymer chains: 4
• Total formula weight: 44238.26

Authors

Burak, M.J.,Guja, K.E.,Garcia-Diaz, M. (deposition date: 2016-03-01, release date: 2016-08-17, Last modification date: 2024-03-06)

• Primary citation: Burak, M.J.,Guja, K.E.,Hambardjieva, E.,Derkunt, B.,Garcia-Diaz, M.; A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG.; Embo J., 35:2045-2059, 2016; PubMed: 27481934; DOI: 10.15252/embj.201694332

Experimental method

X-RAY DIFFRACTION (2.15 Å)