5IFD
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4721 1-(4-fluorophenyl)-1H-imidazole
Summary for 5IFD
Entry DOI | 10.2210/pdb5ifd/pdb |
Related | 4iuj 5ieq 5IF2 5IF5 5IF7 5IF8 5IFB 5IFC |
Descriptor | Polymerase acidic protein, 1-(4-fluorophenyl)-1H-imidazole, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | niaid, structural genomics, flu, fragment screening, std nmr, seattle structural genomics center for infectious disease, ssgcid, viral protein |
Biological source | Influenza A virus (strain A/Wilson-Smith/1933 H1N1) |
Cellular location | Host cytoplasm: P15659 |
Total number of polymer chains | 1 |
Total formula weight | 53337.02 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2016-02-25, release date: 2017-02-22, Last modification date: 2024-03-06) |
Primary citation | Pierce, P.,Muruthi, M.M.,Abendroth, J.,Moen, S.O.,Begley, D.W.,Davies, D.R.,Marathias, V.M.,Staker, B.L.,Myler, P.J.,Lorimer, D.D.,Edwards, T.E. Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
Download full validation report