5I49

RNA Editing TUTase 1 from Trypanosoma brucei in complex with UTP analog UMPNPP

Summary for 5I49

• Entry DOI: 10.2210/pdb5i49/pdb
• Related: 5HZD
• Descriptor: 3' terminal uridylyl transferase, ZINC ION, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... (5 entities in total)
• Functional Keywords: rna editing tutase1, transferase, trypanosoma brucei
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 1
• Total formula weight: 58224.39

Authors

Thore, S.,Rajappa, L.T. (deposition date: 2016-02-11, release date: 2016-11-09, Last modification date: 2024-01-10)

• Primary citation: Rajappa-Titu, L.,Suematsu, T.,Munoz-Tello, P.,Long, M.,Demir, O.,Cheng, K.J.,Stagno, J.R.,Luecke, H.,Amaro, R.E.,Aphasizheva, I.,Aphasizhev, R.,Thore, S.; RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.; Nucleic Acids Res., 44:10862-10878, 2016; PubMed: 27744351; DOI: 10.1093/nar/gkw917

Experimental method

X-RAY DIFFRACTION (1.8 Å)