5HZH
Crystal structure of photoinhibitable Rac1 containing C450A mutant LOV2 domain
Summary for 5HZH
Entry DOI | 10.2210/pdb5hzh/pdb |
Descriptor | Ras-related C3 botulinum toxin substrate 1,NPH1-1,Ras-related C3 botulinum toxin substrate 1, GUANOSINE-5'-TRIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | signaling protein, photoswitch, chimera |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63000 |
Total number of polymer chains | 1 |
Total formula weight | 38150.24 |
Authors | Tarnawski, M.,Dagliyan, O.,Chu, P.H.,Shirvanyants, D.,Dokholyan, N.V.,Hahn, K.M.,Schlichting, I. (deposition date: 2016-02-02, release date: 2016-12-21, Last modification date: 2024-01-10) |
Primary citation | Dagliyan, O.,Tarnawski, M.,Chu, P.H.,Shirvanyants, D.,Schlichting, I.,Dokholyan, N.V.,Hahn, K.M. Engineering extrinsic disorder to control protein activity in living cells. Science, 354:1441-1444, 2016 Cited by PubMed: 27980211DOI: 10.1126/science.aah3404 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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