5HC1

Structure of EAV NSP11 H141A mutant at 3.10A

Summary for 5HC1

• Entry DOI: 10.2210/pdb5hc1/pdb
• Related: 5HBZ
• Descriptor: Non-structural protein 11 (2 entities in total)
• Functional Keywords: nsp11, equine arteritis virus, endoribonuclease, nonstructural protein 11, nidovirus, nf-kappab, hydrolase
• Biological source: Equine arteritis virus Bucyrus (EAV)
• Cellular location: Nsp1 papain-like cysteine proteinase: Host nucleus. Nsp2 cysteine proteinase: Host membrane ; Multi-pass membrane protein . Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 5-6-7: Host membrane ; Multi-pass membrane protein . 3C-like serine proteinase: Host cytoplasm . RNA-directed RNA polymerase: Host cytoplasm, host perinuclear region . Helicase: Host cytoplasm, host perinuclear region : P19811
• Total number of polymer chains: 4
• Total formula weight: 97058.82

Authors

Zhang, M.F.,Chen, Z.Z. (deposition date: 2016-01-04, release date: 2016-10-12, Last modification date: 2023-11-08)

• Primary citation: Zhang, M.,Li, X.,Deng, Z.,Chen, Z.,Liu, Y.,Gao, Y.,Wu, W.,Chen, Z.; Structural Biology of the Arterivirus nsp11 Endoribonucleases.; J. Virol., 91:-, 2017; PubMed: 27795409; DOI: 10.1128/JVI.01309-16

Experimental method

X-RAY DIFFRACTION (3.1 Å)