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5HAP

OXA-48 beta-lactamase - S70A mutant

Summary for 5HAP
Entry DOI10.2210/pdb5hap/pdb
Related5HAI 5HAQ 5HAR
DescriptorBeta-lactamase, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... (10 entities in total)
Functional Keywordshydrolase, serine beta-lactamase
Biological sourceKlebsiella pneumoniae
Total number of polymer chains2
Total formula weight57935.00
Authors
Stojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Prasad, B.V.V.,Palzkill, T.G. (deposition date: 2015-12-30, release date: 2016-09-07, Last modification date: 2023-11-15)
Primary citationStojanoski, V.,Adamski, C.J.,Hu, L.,Mehta, S.C.,Sankaran, B.,Zwart, P.,Prasad, B.V.,Palzkill, T.
Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine beta-Lactamases by Relieving Steric Strain.
Biochemistry, 55:2479-2490, 2016
Cited by
PubMed: 27073009
DOI: 10.1021/acs.biochem.6b00056
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.89 Å)
Structure validation

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