5H6V

Structure of Zika virus protease in complex with a dipeptide inhibitor

Summary for 5H6V

• Entry DOI: 10.2210/pdb5h6v/pdb
• NMR Information: BMRB: 26933
• Descriptor: Genome polyprotein, (S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, ... (4 entities in total)
• Functional Keywords: serine protease, non-structural protein 3, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Zika virus (ZIKV); More
• Total number of polymer chains: 2
• Total formula weight: 25088.29

Authors

Zhang, Z.,Chen, M. (deposition date: 2016-11-15, release date: 2017-06-14, Last modification date: 2023-11-08)

• Primary citation: Li, Y.,Zhang, Z.,Phoo, W.W.,Loh, Y.R.,Wang, W.,Liu, S.,Chen, M.W.,Hung, A.W.,Keller, T.H.,Luo, D.,Kang, C.; Structural Dynamics of Zika Virus NS2B-NS3 Protease Binding to Dipeptide Inhibitors; Structure, 25:1242-1250.e3, 2017; PubMed: 28689970; DOI: 10.1016/j.str.2017.06.006

Experimental method

X-RAY DIFFRACTION (2.422 Å)