5GUC

Crystal structure of CotB2 (apo form) from Streptomyces melanosporofaciens

Summary for 5GUC

• Entry DOI: 10.2210/pdb5guc/pdb
• Related: 5GUE
• Descriptor: Cyclooctat-9-en-7-ol synthase, FORMIC ACID (3 entities in total)
• Functional Keywords: terpene cyclase fold, diterpene cyclase, lyase, biosynthetic protein
• Biological source: Streptomyces melanosporofaciens
• Total number of polymer chains: 2
• Total formula weight: 76476.31

Authors

Tomita, T.,Kim, S.-Y.,Ozaki, T.,Yoshida, A.,Kuzuyama, T.,Nishiyama, M. (deposition date: 2016-08-28, release date: 2017-06-07, Last modification date: 2024-03-20)

• Primary citation: Tomita, T.,Kim, S.-Y.,Teramoto, K.,Meguro, A.,Ozaki, T.,Yoshida, A.,Motoyoshi, Y.,Mori, N.,Ishigami, K.,Watanabe, H.,Nishiyama, M.,Kuzuyama, T.; Structural Insights into the CotB2-Catalyzed Cyclization of Geranylgeranyl Diphosphate to the Diterpene Cyclooctat-9-en-7-ol; ACS Chem. Biol., 12:1621-1628, 2017; PubMed: 28463490; DOI: 10.1021/acschembio.7b00154

Experimental method

X-RAY DIFFRACTION (1.8 Å)