5GTC

Crystal structure of complex between DMAP-SH conjugated with a Kaposi's sarcoma herpesvirus LANA peptide (5-15) and nucleosome core particle

Summary for 5GTC

• Entry DOI: 10.2210/pdb5gtc/pdb
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (8 entities in total)
• Functional Keywords: dna binding, nucleus, histone fold, chromatin formation, nucleosome, structural protein-dna complex, structural protein/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P68431 P62805 P04908 P06899
• Total number of polymer chains: 11
• Total formula weight: 203880.50

Authors

Arimura, Y.,Kato, D.,Suto, H.,Kurumizaka, H.,Kawashima, S.A.,Yamatsugu, K.,Kanai, M. (deposition date: 2016-08-19, release date: 2017-06-28, Last modification date: 2023-11-08)

• Primary citation: Amamoto, Y.,Aoi, Y.,Nagashima, N.,Suto, H.,Yoshidome, D.,Arimura, Y.,Osakabe, A.,Kato, D.,Kurumizaka, H.,Kawashima, S.A.,Yamatsugu, K.,Kanai, M.; Synthetic Posttranslational Modifications: Chemical Catalyst-Driven Regioselective Histone Acylation of Native Chromatin.; J. Am. Chem. Soc., 139:7568-7576, 2017; PubMed: 28534629; DOI: 10.1021/jacs.7b02138

Experimental method

X-RAY DIFFRACTION (2.7 Å)