5G3J
Discovery of New Selective Glucocorticoid Receptor Agonist Leads
Summary for 5G3J
Entry DOI | 10.2210/pdb5g3j/pdb |
Descriptor | GLUCOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 2, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... (6 entities in total) |
Functional Keywords | dna binding protein, glucocorticoid receptor, nuclear hormone receptor, steroid receptor, signaling protein, ligand complex, peptide complex |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 35027.40 |
Authors | Berger, M.,Edman, K.,Wissler, L.,Neuhaus, R.,Rehwinkel, H.,Schacke, H.,Jaroch, S. (deposition date: 2016-04-27, release date: 2017-02-15, Last modification date: 2024-01-10) |
Primary citation | Berger, M.,Rehwinkel, H.,Schmees, N.,Schacke, H.,Edman, K.,Wissler, L.,Reichel, A.,Jaroch, S. Discovery of New Selective Glucocorticoid Receptor Agonist Leads. Bioorg.Med.Chem.Lett., 27:437-, 2017 Cited by PubMed: 28043796DOI: 10.1016/J.BMCL.2016.12.047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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