5FWE
JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE
Summary for 5FWE
Entry DOI | 10.2210/pdb5fwe/pdb |
Descriptor | LYSINE-SPECIFIC DEMETHYLASE 4A, SYNTHETIC PEPTIDE, NICKEL (II) ION, ... (8 entities in total) |
Functional Keywords | jmjd2a, oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, double-stranded beta helix, dsbh, facial triad, demethylase, histone, jmjc domain, metal binding protein, epigenetic and transcription regulation, chromatin regulator, hydroxylation |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 91992.96 |
Authors | Chowdhury, R.,Walport, L.J.,Schofield, C.J. (deposition date: 2016-02-15, release date: 2016-04-06, Last modification date: 2024-01-10) |
Primary citation | Walport, L.J.,Hopkinson, R.J.,Chowdhury, R.,Schiller, R.,Ge, W.,Kawamura, A.,Schofield, C.J. Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases. Nat.Commun., 7:11974-, 2016 Cited by PubMed: 27337104DOI: 10.1038/NCOMMS11974 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report