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5FMI

Human Bak Q77L

Summary for 5FMI
Entry DOI10.2210/pdb5fmi/pdb
Related5FMJ 5FMK
DescriptorBCL-2 HOMOLOGOUS ANTAGONIST/KILLER, ZINC ION (3 entities in total)
Functional Keywordsbak, apoptosis, bcl-2 family
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMitochondrion membrane ; Single-pass membrane protein : Q16611
Total number of polymer chains1
Total formula weight18504.77
Authors
Fairlie, W.D.,Lee, E.F.,Smith, B.J. (deposition date: 2015-11-06, release date: 2016-06-01, Last modification date: 2024-01-10)
Primary citationLee, E.F.,Grabow, S.,Chappaz, S.,Dewson, G.,Hockings, C.,Kluck, R.M.,Gray, D.H.,Witkowski, M.T.,Evangelista, M.,Pettikiriarachchi, A.,Bouillet, P.,Lane, R.M.,Czabotar, P.E.,Colman, P.M.,Smith, B.J.,Kile, B.T.,Fairlie, W.D.
Physiological Restraint of Bak by Bcl-Xl is Essential for Cell Survival.
Genes Dev., 30:1240-, 2016
Cited by
PubMed: 27198225
DOI: 10.1101/GAD.279414.116
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.491 Å)
Structure validation

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