5FEH

Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody

Summary for 5FEH

• Entry DOI: 10.2210/pdb5feh/pdb
• Descriptor: PCT64_26 Fab light chain, PCT64_26 Fab heavy chain, SULFATE ION, ... (5 entities in total)
• Functional Keywords: hiv, broadly neutralizing antibody, v1/v2, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 150003.92

Authors

Murrell, S.,Wilson, I.A. (deposition date: 2015-12-17, release date: 2017-08-16, Last modification date: 2023-09-27)

• Primary citation: Landais, E.,Murrell, B.,Briney, B.,Murrell, S.,Rantalainen, K.,Berndsen, Z.T.,Ramos, A.,Wickramasinghe, L.,Smith, M.L.,Eren, K.,de Val, N.,Wu, M.,Cappelletti, A.,Umotoy, J.,Lie, Y.,Wrin, T.,Algate, P.,Chan-Hui, P.Y.,Karita, E.,Ward, A.B.,Wilson, I.A.,Burton, D.R.,Smith, D.,Pond, S.L.K.,Poignard, P.; HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage.; Immunity, 47:990-1003.e9, 2017; PubMed: 29166592; DOI: 10.1016/j.immuni.2017.11.002

Experimental method

X-RAY DIFFRACTION (3.1 Å)