5EYO
The crystal structure of the Max bHLH domain in complex with 5-carboxyl cytosine DNA
Summary for 5EYO
Entry DOI | 10.2210/pdb5eyo/pdb |
Descriptor | Protein max, DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3') (3 entities in total) |
Functional Keywords | bhlh protein, 5-carboxylcytosine dna, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 30868.06 |
Authors | Wang, D.,Hashimoto, H.,Zhang, X.,Cheng, X. (deposition date: 2015-11-25, release date: 2016-12-14, Last modification date: 2023-09-27) |
Primary citation | Wang, D.,Hashimoto, H.,Zhang, X.,Barwick, B.G.,Lonial, S.,Boise, L.H.,Vertino, P.M.,Cheng, X. MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma. Nucleic Acids Res., 45:2396-2407, 2017 Cited by PubMed: 27903915DOI: 10.1093/nar/gkw1184 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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