5EDB

human fatty acid binding protein 4 in complex with 6-Chloro-2-methyl-4-phenyl-quinoline-3-carboxylic acid at 1.18A

Summary for 5EDB

• Entry DOI: 10.2210/pdb5edb/pdb
• Descriptor: Fatty acid-binding protein, adipocyte, 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid (3 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P15090
• Total number of polymer chains: 1
• Total formula weight: 15262.86

Authors

Rudolph, M.G.,Ehler, A. (deposition date: 2015-10-21, release date: 2016-03-09)

• Primary citation: Kuhn, B.,Guba, W.,Hert, J.,Banner, D.,Bissantz, C.,Ceccarelli, S.,Haap, W.,Korner, M.,Kuglstatter, A.,Lerner, C.,Mattei, P.,Neidhart, W.,Pinard, E.,Rudolph, M.G.,Schulz-Gasch, T.,Woltering, T.,Stahl, M.; A Real-World Perspective on Molecular Design.; J.Med.Chem., 59:4087-4102, 2016; PubMed: 26878596; DOI: 10.1021/acs.jmedchem.5b01875

Experimental method

X-RAY DIFFRACTION (1.18 Å)