5E5G

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with D-tryptophan bound in the tryptophan and phenylalanine binding sites

Summary for 5E5G

• Entry DOI: 10.2210/pdb5e5g/pdb
• Related: 2YPQ 3KGF 3NUE 3NV8 5E2L 5E40 5E4N 5E7Z
• Descriptor: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, SULFATE ION, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: allosteric regulation, 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase, transferase, shikimate pathway
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 103063.88

Authors

Reichau, S.,Jiao, W.,Parker, E.J. (deposition date: 2015-10-08, release date: 2016-06-01, Last modification date: 2023-11-15)

• Primary citation: Reichau, S.,Blackmore, N.J.,Jiao, W.,Parker, E.J.; Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.; Plos One, 11:e0152723-e0152723, 2016; PubMed: 27128682; DOI: 10.1371/journal.pone.0152723

Experimental method

X-RAY DIFFRACTION (1.95 Å)